2022 Lexus RX 350

The 2022 Lexus RX 350 is a five-seat SUV with V6 power, premium fuel recommendations, and a calm, practical profile for daily driving around North Fulton. At Nalley Lexus Roswell, located at 980 Mansell Road in Roswell, shoppers can explore how this Lexus fits their needs, compare it with related Lexus models, and connect with live new inventory as vehicles arrive on a rolling basis. The dealership sits just off GA-400 at Exit 8, between Alpharetta and historic Roswell, near the Canton Street district, Wills Park, and Chattahoochee River National Recreation Area. This page brings together the RX 350’s core specifications, ownership considerations, and ways to begin the buying process locally.

Starting MSRP

$45,920

Horsepower

295 hp

EPA MPG

19–20 city / 26–27 hwy

Seating

5 seats

Fuel

Premium Unleaded (Recommended)

Body Style

SUV

How the 2022 Lexus RX 350 Compares With the Lexus Lineup

Pricing, power, fuel economy, seating practicality, and towing capacity can shape a shopper’s choice among related Lexus SUVs. The 2022 Lexus RX 350 starts at $45,920, and MSRP excludes tax, title, registration and dealer fees.

Compared with the 2022 Lexus RX 450h, the RX 350 starts at $45,920 versus $48,720 and produces 295 hp versus 308 hp. The RX 450h’s 31 city / 28 hwy EPA MPG favors shoppers prioritizing the quoted city fuel-economy figure, while the RX 350 suits those seeking the lower starting MSRP and conventional V6 configuration.

Compared with the 2022 Lexus RX 350L, the RX 350 starts at $45,920 versus $48,750 and makes 295 hp versus 290 hp. The RX 350L offers 18–19 city / 25–26 hwy EPA MPG and a maximum towing capacity of 3,500 lbs, which may appeal to shoppers focused on its quoted towing capability, while the RX 350 favors the lower starting price and higher horsepower figure.

Compared with the 2022 Lexus NX 350, the RX 350 starts at $45,920 versus $41,950 and produces 295 hp versus 275 hp. The NX 350 quotes 22 city / 28–29 hwy EPA MPG and a maximum towing capacity of 2,000 lbs, favoring shoppers focused on those efficiency and towing figures, while the RX 350 offers more horsepower and a larger SUV profile.

2022 Lexus RX 350 Specifications and Configuration

The 2022 Lexus RX 350 uses a 3.5-liter V6 engine with 3,457 cc of displacement, an automatic transmission, and eight transmission speeds. It produces 295 hp at 6,300 rpm and 268 lb-ft of torque at 4,700 rpm.

EPA fuel economy ranges from 19 to 20 city MPG and 26 to 27 highway MPG across the two trims of this model. Premium unleaded fuel is recommended, and the body style is SUV with seating for five.

The destination charge is $1,075. Its starting MSRP range across the two trims is $45,920 to $50,800, with $45,920 as this model’s starting price.

Buying a 2022 Lexus RX 350 in Roswell

Nalley Lexus Roswell serves shoppers throughout Roswell, Alpharetta, and North Fulton from 980 Mansell Road. Its location along North Fulton’s premier automotive corridor places the dealership near GA-400, the Alpharetta Tech Corridor, Perimeter Center, Willow Springs, Horseshoe Bend, and Downtown Roswell.

To follow changing vehicle availability, search inventory through the dealership’s live listings. The store receives vehicles on a rolling basis, so online inventory is the practical starting point before planning a visit.

Shoppers considering a current vehicle can also explore trade-in options as part of the purchase process. Nalley Lexus Roswell provides a local point of contact for questions at (770) 284-8580.

What to Weigh Before Buying

Consider how the RX 350’s five-seat layout fits regular passengers, cargo routines, and the roads traveled most often. Its 19 to 20 city MPG and 26 to 27 highway MPG ranges offer useful context for shoppers balancing urban commuting with longer North Fulton drives.

Powertrain preference is another important consideration. The RX 350 uses a V6 and recommends premium unleaded fuel, while the RX 450h comparison model uses the fuel description Premium Unleaded (Recommended) and quotes a different economy figure. Comparing the RX 350 with the RX 350L or NX 350 can also clarify whether the quoted towing capacity or starting MSRP matters more to the purchase.

Remember that the $1,075 destination charge is separate from MSRP, and prices exclude tax, title, registration and dealer fees. A live inventory review and an in-person drive can help connect the specifications with everyday use.