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Nalley Lexus Roswell
2022 Lexus RX 450h
Now available at Nalley Lexus Roswell in Roswell, GA
- Starting MSRP$48,720
- Horsepower308 hp
- EPA MPG31 city / 28 hwy
- FuelPremium Unleaded (Recommended)

The 2022 Lexus RX 450h brings a 308-horsepower hybrid powertrain, premium fuel recommendations, and SUV practicality to shoppers visiting Nalley Lexus Roswell in Roswell, GA. This page covers its trim pricing, fuel economy, mechanical configuration, comparisons with related Lexus models, and ways to explore purchasing or arranging an in-person visit at 980 Mansell Road, conveniently positioned between Alpharetta and historic Roswell near GA-400 Exit 8.
- Starting MSRP
- $48,720
- Horsepower
- 308 hp
- EPA MPG
- 31 city / 28 hwy
- Fuel
- Premium Unleaded (Recommended)
- Body Style
- SUV
How the 2022 Lexus RX 450h Compares With the Lexus Lineup
Pricing, power, fuel economy, seating, towing capability, and body configuration can all shape a Lexus SUV decision. The 2022 Lexus RX 450h starts at $48,720, and MSRP excludes tax, title, registration and dealer fees.
| Spec | 2022 Lexus RX 450h | 2022 Lexus RX 350L | 2022 Lexus RX 350 | 2022 Lexus RX 450hL |
|---|---|---|---|---|
| Starting MSRP | $48,720 | $48,750 | $45,920 | $52,110 |
| Horsepower | 308 hp | 290 hp | 295 hp | 308 hp |
| EPA MPG | 31 city / 28 hwy | 18–19 city / 25–26 hwy | 19–20 city / 26–27 hwy | 29 city / 28 hwy |
| Fuel | Premium Unleaded (Recommended) | Premium Unleaded (Recommended) | Premium Unleaded (Recommended) | Premium Unleaded (Recommended) |
Manufacturer figures for the model year shown; a range spans that model's trims. Starting MSRP excludes tax, title, registration, and dealer fees.
Compared with the 2022 Lexus RX 350L, the RX 450h starts at $48,720 versus $48,750 and produces 308 hp versus 290 hp. Its 31 city / 28 highway MPG figures favor shoppers focused on efficiency, while the RX 350L's 3,500-lb maximum towing figure may suit buyers prioritizing towing capability.
Compared with the 2022 Lexus RX 350, the RX 450h starts at $48,720 versus $45,920 and makes 308 hp versus 295 hp. The RX 450h's 31 city / 28 highway MPG favors efficiency-minded drivers, while the RX 350's 19–20 city / 26–27 highway EPA MPG and five-seat configuration may appeal to shoppers seeking a lower starting price and a straightforward five-seat SUV.
Compared with the 2022 Lexus RX 450hL, the RX 450h starts at $48,720 versus $52,110, while both produce 308 hp. The RX 450h's 31 city / 28 highway MPG differs from the RX 450hL's 29 city / 28 highway MPG, giving shoppers a way to weigh starting price and city efficiency against the related model's configuration.
Specifications and Configuration
The 2022 Lexus RX 450h is a premium SUV with a 3.5-liter V6 engine layout, automatic transmission, and continuously variable transmission speeds. Premium unleaded is recommended, and peak power arrives at 6,000 rpm.
Across the model's three trims, starting MSRP ranges from $48,720 to $54,520, with a $1,075 destination charge. The F SPORT trim starts at $52,200, while F SPORT Handling starts at $54,520. Fuel economy is rated at 31 city MPG and 28 highway MPG.
Buying a 2022 Lexus RX 450h in Roswell
Nalley Lexus Roswell is located at 980 Mansell Road in the heart of North Fulton's premier automotive corridor. The dealership sits between Alpharetta and historic Roswell, just off GA-400 at Exit 8, making it convenient for commuters, families, and shoppers traveling through the Alpharetta Tech Corridor, Perimeter Center, or nearby North Fulton neighborhoods.
Inventory changes on a rolling basis, so shoppers can search inventory for current vehicle listings. Nalley Lexus Roswell is also close to Canton Street, Wills Park, and the Chattahoochee River National Recreation Area, fitting naturally into errands, school runs, and weekend travel around Roswell.
What to Weigh Before Buying
Consider how the RX 450h's 31 city MPG, 28 highway MPG, 308 hp, premium fuel recommendation, and continuously variable transmission align with daily driving needs. Trim selection also affects starting MSRP, with the F SPORT and F SPORT Handling versions positioned above the model's $48,720 starting point.
It can also help to compare the RX 450h with related Lexus SUVs according to the priorities that matter most, including starting price, city fuel economy, highway fuel economy, horsepower, seating, and towing capability. A live inventory search and an in-person visit can provide the next step for evaluating the model.
Frequently Asked Questions
7 common questions answered
Is the 2022 Lexus RX 450h a hybrid SUV?Yes, the 2022 Lexus RX 450h is a hybrid SUV with 308 hp.
It uses a 3.5-liter V6 engine layout, automatic transmission, and continuously variable transmission speeds. Premium unleaded is recommended.
- SUV body style
- 308 hp
- 3.5-liter engine
How much does the 2022 Lexus RX 450h cost?The 2022 Lexus RX 450h has a starting MSRP of $48,720.
Across its three trims, starting MSRP ranges from $48,720 to $54,520, with a $1,075 destination charge. MSRP excludes tax, title, registration and dealer fees.
- F SPORT starts at $52,200
- F SPORT Handling starts at $54,520
- Destination charge is $1,075
What fuel economy does the 2022 Lexus RX 450h get?The 2022 Lexus RX 450h is rated at 31 city MPG and 28 highway MPG.
Those figures make city efficiency a central part of the RX 450h's configuration. Premium unleaded is recommended for its 3.5-liter V6 engine.
- 31 city MPG
- 28 highway MPG
- Premium unleaded recommended
How much horsepower does the 2022 Lexus RX 450h have?The 2022 Lexus RX 450h produces 308 hp.
Peak power arrives at 6,000 rpm. The powertrain is paired with an automatic transmission and continuously variable transmission speeds.
- 308 hp
- Peak power at 6,000 rpm
- V6 engine layout
Should I choose the RX 450h or the RX 350?Choose between them by weighing the RX 450h's 31 city / 28 highway MPG and 308 hp against the RX 350's lower $45,920 starting MSRP.
The 2022 Lexus RX 350 produces 295 hp and is rated at 19–20 city / 26–27 highway EPA MPG, with seating for five. The RX 450h starts at $48,720 and produces 308 hp.
- RX 450h starting MSRP: $48,720
- RX 350 starting MSRP: $45,920
- RX 350 seats five
Can I compare the RX 450h with the RX 350L?Yes, the RX 450h and RX 350L differ in price, horsepower, fuel economy, and towing capability.
The RX 350L starts at $48,750 and produces 290 hp, with EPA MPG of 18–19 city / 25–26 highway. Its maximum towing capacity is 3,500 lbs, while the RX 450h starts at $48,720 and produces 308 hp.
- RX 450h: 31 city / 28 highway MPG
- RX 350L: 18–19 city / 25–26 highway EPA MPG
- RX 350L maximum towing: 3,500 lbs
How can I see a 2022 Lexus RX 450h near Roswell?Start by searching current inventory at Nalley Lexus Roswell in Roswell, GA.
The dealership is located at 980 Mansell Road near GA-400 Exit 8. Inventory changes on a rolling basis, so an online search is a practical way to begin planning an in-person visit.
- Located in Roswell, GA
- Near Alpharetta and historic Roswell
- Search live inventory before visiting